Intravenous immunoglobulin therapy in pregnant patients affected with systemic lupus erythematosus and recurrent spontaneous abortion.

@article{Perricone2008IntravenousIT,
  title={Intravenous immunoglobulin therapy in pregnant patients affected with systemic lupus erythematosus and recurrent spontaneous abortion.},
  author={Roberto Salvatore Perricone and Caterina De Carolis and B Kr{\"o}egler and Ezequiel Greco and Roberto Giacomelli and Paola Cipriani and Luigi Fontana and Carlo Perricone},
  journal={Rheumatology},
  year={2008},
  volume={47 5},
  pages={
          646-51
        }
}
OBJECTIVES We aimed to test the maternal and fetal outcome of SLE patients who suffered from recurrent spontaneous abortion (RSA) treated with intravenous immunoglobulin (IVIg) alone during pregnancy and whether the clinical response to IVIg treatment is accompanied by modifications of SLE-associated antibodies and of complement levels. METHODS Twelve SLE-RSA pregnant patients were treated with high-dose IVIg and compared with 12 SLE-RSA pregnant patients treated with prednisolone and NSAIDs… CONTINUE READING

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