Intravenous immune globulin in the therapy of myocarditis and acute cardiomyopathy.

  title={Intravenous immune globulin in the therapy of myocarditis and acute cardiomyopathy.},
  author={Dennis M. McNamara and Warren D Rosenblum and Karen M Janosko and Matthias Trost and F S Villaneuva and Anthony Jack Demetris and Srinivas Murali and Arthur M Feldman},
  volume={95 11},
BACKGROUND Although an autoimmune pathogenesis has been postulated for dilated cardiomyopathy, immunosuppressive therapy has not been shown to be effective in clinical trials. Immune modulatory therapy with immune globulin is an effective therapy for Kawasaki disease in children, and recent data suggest that it improves ventricular function in children with new-onset dilated cardiomyopathies. The role of immune globulin therapy in adults with this disorder has not previously been evaluated… CONTINUE READING


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