Intravenous emulsified halogenated anesthetics produce acute and delayed preconditioning against myocardial infarction in rabbits.

@article{Chiari2004IntravenousEH,
  title={Intravenous emulsified halogenated anesthetics produce acute and delayed preconditioning against myocardial infarction in rabbits.},
  author={Pascal C Chiari and Paul S. Pagel and Katsuya Tanaka and John G. Krolikowski and Lynda M. Ludwig and Raul A Trillo and Navneet Puri and Judy R. Kersten and David C. Warltier},
  journal={Anesthesiology},
  year={2004},
  volume={101 5},
  pages={
          1160-6
        }
}
BACKGROUND Preconditioning against myocardial infarction by volatile anesthetics is well known. The authors tested the hypothesis that new emulsified formulations of halogenated anesthetics administered intravenously reduce myocardial infarct size when administered either 1 or 24 h before prolonged ischemia and reperfusion. METHODS Pentobarbital-anesthetized rabbits (n = 39) were instrumented for measurement of hemodynamics and randomly assigned to receive intravenous saline (control), lipid… CONTINUE READING

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