Intravenous drug self-administration in mice: practical considerations.

@article{Thomsen2007IntravenousDS,
  title={Intravenous drug self-administration in mice: practical considerations.},
  author={Morgane Thomsen and Simon Caine},
  journal={Behavior genetics},
  year={2007},
  volume={37 1},
  pages={101-18}
}
Chronic intravenous drug self-administration in rodents is a useful procedure for predicting the abuse liability of novel drugs in humans, for evaluating candidate treatments for drug abuse and dependence, and for studying the biological basis of addiction. Despite the technical challenge in achieving chronic self-administration behavior in the mouse species, researchers are increasingly using genetically engineered mice to investigate the role of specific genes in abuse-related effects of… CONTINUE READING

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