Intravenous cyclophosphamide is the drug of choice for steroid dependent nephrotic syndrome.

@article{Bircan2003IntravenousCI,
  title={Intravenous cyclophosphamide is the drug of choice for steroid dependent nephrotic syndrome.},
  author={Zelal Ekinci Bircan and Bulent Kara},
  journal={Pediatrics international : official journal of the Japan Pediatric Society},
  year={2003},
  volume={45 1},
  pages={
          65-7
        }
}
BACKGROUND Steroid dependency is a major problem seen after therapy for idiopathic nephrotic syndrome in childhood. Although there is consensus about the usage of cyclophosphamide (CYC) in frequent relapsers, there is still a controversy concerning its usage in steroid-dependent nephrotic syndrome (SDNS). METHODS In the present study, nineteen children with SDNS were treated with CYC: ten via the intravenous (i.v.) route, and nine via the oral route. Remission was then maintained with… CONTINUE READING
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