Intravenous butyrate and healing of colonic anastomoses in the rat.

@article{Rolandelli1997IntravenousBA,
  title={Intravenous butyrate and healing of colonic anastomoses in the rat.},
  author={Rolando H. Rolandelli and Michael A. Buckmire and Kara A Bernstein},
  journal={Diseases of the colon and rectum},
  year={1997},
  volume={40 1},
  pages={67-70}
}
PURPOSE Intracolonic infusions of short chain fatty acids promote healing of colonic anastomoses. Because the intravenous route may have wider clinical application, we studied the effect of intravenous n-butyrate on the mechanical strength of colonic anastomoses in the rat. METHODS After placement of an indwelling intravenous catheter, the descending colon was transected and an anastomosis was performed. Rats were then randomized to receive total parenteral nutrition (TPN group; n = 15) or… CONTINUE READING

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