Intravenous butorphanol administration reduces intrathecal morphine-induced pruritus after cesarean delivery: a randomized, double-blind, placebo-controlled study

@article{Wu2012IntravenousBA,
  title={Intravenous butorphanol administration reduces intrathecal morphine-induced pruritus after cesarean delivery: a randomized, double-blind, placebo-controlled study},
  author={Zhen Wu and Mingjian Kong and Ning Wang and Roderick J. Finlayson and Quang Hieu De Tran},
  journal={Journal of Anesthesia},
  year={2012},
  volume={26},
  pages={752-757}
}
Pruritus associated with intrathecal opioid administration is a common side effect. There is evidence that κ-opioid receptor agonists have antipruritic activity. Butorphanol has agonist actions at both κ-opioid and μ-opioid receptors. This study was designed to evaluate the antipruritic efficacy of butorphanol after intrathecal morphine administration in the setting of a randomized, double-blind study of parturients undergoing cesarean section. Ninety-one women who received combined spinal… CONTINUE READING
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