Intravenous Ondansetron and the QT Interval in Adult Emergency Department Patients: An Observational Study.

@article{Moffett2016IntravenousOA,
  title={Intravenous Ondansetron and the QT Interval in Adult Emergency Department Patients: An Observational Study.},
  author={Peter M. Moffett and Laquisha Cartwright and Elizabeth A Grossart and Dustin O'Keefe and Christopher Kang},
  journal={Academic emergency medicine : official journal of the Society for Academic Emergency Medicine},
  year={2016},
  volume={23 1},
  pages={102-5}
}
OBJECTIVES Ondansetron is known to cause QT interval prolongation, but this effect and clinical significance has not been prospectively studied in adult emergency department (ED) patients. The primary objective was to determine the mean maximal corrected QT interval (QTc) prolongation after intravenous (IV) administration of 4 mg of ondansetron. The secondary objective was to report any serious adverse cardiac electrical events. METHODS This was a prospective, observational, single-center… CONTINUE READING
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