Intravenous N-acetylcystine: the treatment of choice for paracetamol poisoning.

@article{Prescott1979IntravenousNT,
  title={Intravenous N-acetylcystine: the treatment of choice for paracetamol poisoning.},
  author={L. Prescott and R. Illingworth and J. Critchley and M. J. Stewart and R. D. Adam and A. Proudfoot},
  journal={British Medical Journal},
  year={1979},
  volume={2},
  pages={1097 - 1100}
}
One hundred cases of severe paracetamol poisoning were treated with intravenous N-acetylcysteine (acetyl-cysteine). There was virtually complete protection against liver damage in 40 patients treated within eight hours after ingestion (mean maximum serum alanine transaminase activity 27 IU/1). Only one out of 62 patients treated within 10 hours developed severe liver damage compared with 33 out of 57 patients (58%) studied retrospectively who received supportive treatment alone. Early treatment… Expand
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