Intravenous Abuse of Propylhexedrine (Benzedrex®) and the Risk of Brainstem Dysfunction in Young Adults

  title={Intravenous Abuse of Propylhexedrine (Benzedrex{\textregistered}) and the Risk of Brainstem Dysfunction in Young Adults},
  author={Luis R. Fornazzari and Peter L. Carlen and Bhushan M. Kapur},
  journal={Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques},
  pages={337 - 339}
  • L. Fornazzari, P. Carlen, B. Kapur
  • Published 1 November 1986
  • Medicine, Psychology
  • Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
ABSTRACT: In 1949, amphetamine sulfate was replaced by propylhexedrine in the nasal decongestant agent Benzedrex® because of psychosis, sudden death, and widespread abuse. Propylhexedrine is not without risks, and reported cases of psychosis, myocardial infarction, pulmonary vascular disease and pulmonary hypertension, and sudden death are well documented in the medical literature. We are reporting 2 cases of definite brainstem dysfunction and 5 cases of transient diplopia secondary to IV abuse… 

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