Intravascular inertial cavitation activity detection and quantification in vivo with Optison.

@article{Tu2006IntravascularIC,
  title={Intravascular inertial cavitation activity detection and quantification in vivo with Optison.},
  author={Junyang Tu and Joo Ha Hwang and Thomas J. Matula and Andrew A. Brayman and Lawrence A. Crum},
  journal={Ultrasound in medicine & biology},
  year={2006},
  volume={32 10},
  pages={
          1601-9
        }
}
Inertial cavitation (IC) is an important mechanism by which ultrasound (US)-induced bioeffects can be produced. It has been reported that US-induced in vitro mechanical bioeffects with the presence of ultrasound contrast agents (UCAs) are highly correlated with quantified IC "dose" (ICD: cumulated root-mean-squared broadband noise amplitude in the frequency domain). The ICD has also been used to quantify IC activity in ex vivo perfused rabbit ear vessels. The in vivo experiments reported here… CONTINUE READING
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