Intrauterine human chorionic gonadotropin infusion in oocyte donors promotes endometrial synchrony and induction of early decidual markers for stromal survival: a randomized clinical trial.

@article{Strug2016IntrauterineHC,
  title={Intrauterine human chorionic gonadotropin infusion in oocyte donors promotes endometrial synchrony and induction of early decidual markers for stromal survival: a randomized clinical trial.},
  author={Michael R. Strug and Renwei Su and James Everett Young and William G Dodds and Valerie I. Shavell and Patricia D{\'i}az-Gimeno and Maria Ruiz-Alonso and Carlos Sim{\'o}n and Bruce A Lessey and Richard E. Leach and Asgerally Turabally Fazleabas},
  journal={Human reproduction},
  year={2016},
  volume={31 7},
  pages={
          1552-61
        }
}
STUDY QUESTION Does a single intrauterine infusion of human chorionic gonadotropin (hCG) at the time corresponding to a Day 3 embryo transfer in oocyte donors induce favorable molecular changes in the endometrium for embryo implantation? SUMMARY ANSWER Intrauterine hCG was associated with endometrial synchronization between endometrial glands and stroma following ovarian stimulation and the induction of early decidual markers associated with stromal cell survival. WHAT IS KNOWN ALREADY The… CONTINUE READING
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