Intrauterine growth retardation in endothelial nitric oxide synthase-deficient mice is established from early stages of pregnancy.

@article{Pallars2008IntrauterineGR,
  title={Intrauterine growth retardation in endothelial nitric oxide synthase-deficient mice is established from early stages of pregnancy.},
  author={Pilar Pallar{\'e}s and Antonio Gonz{\'a}lez-Bulnes},
  journal={Biology of reproduction},
  year={2008},
  volume={78 6},
  pages={
          1002-6
        }
}
The current study aimed to determine effects of deficiencies in nitric oxide synthase (NOS) 3 on embryo and fetal development by in vivo, noninvasive, real-time ultrasonographic assessment of phenotypic changes in Nos3-knockout pregnant mice and their wild-type counterparts. From Day 4.5 of pregnancy onwards, embryonic vesicle diameters, crown-rump lengths, and trunk diameters were obtained by serial scanning of seven adult pregnant female mice, strain B6.129P2-Nos3(tm1Unc)/J, N9 generation… CONTINUE READING

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