Intratympanic gentamicin therapy for Ménière's disease.

  title={Intratympanic gentamicin therapy for M{\'e}ni{\`e}re's disease.},
  author={Barry E. Hirsch and Donald B Kamerer},
  journal={The American journal of otology},
  volume={18 1},
OBJECTIVE To evaluate the efficacy and toxicity of intratympanic gentamicin therapy for the treatment of Meniere's disease. STUDY DESIGN We compared retrospective case series with historical controls. SETTING A tertiary referral center--the ambulatory clinic at The University of Pittsburgh Medical Center. PATIENTS The study consisted of 28 patients with Meniere's disease who failed conventional medical therapy and were offered gentamicin treatment or surgical intervention. Patients had to… CONTINUE READING