Intratympanic gentamicin for the treatment of unilateral Meniere's disease.

  title={Intratympanic gentamicin for the treatment of unilateral Meniere's disease.},
  author={Daniel M. Kaplan and Julian M. Nedzelski and Joseph M. Chen and David B Shipp},
  journal={The Laryngoscope},
  volume={110 8},
OBJECTIVE To determine the efficacy of intratympanic gentamicin instillation as treatment of incapacitating unilateral Meniere's disease, using a predetermined regimen with a fixed dose. STUDY DESIGN A prospective study from a single institution between 1988 and 1998. METHODS One hundred fourteen patients were enrolled in this study. Gentamicin (26.7 mg/mL) was administered three times daily for 4 consecutive days. The Committee on Hearing and Equilibrium Guidelines for Reporting Treatment… CONTINUE READING