Intratympanic Methylprednisolone for Sudden Sensorineural Hearing Loss: Comprehensive Re Examination of the Model

@article{Piones2015IntratympanicMF,
  title={Intratympanic Methylprednisolone for Sudden Sensorineural Hearing Loss: Comprehensive Re Examination of the Model},
  author={Jeanette S{\'a}enz Pi{\~n}ones and Ithzel Mar{\'i}a Villarreal and Raimon Garc{\'i}a Chiller{\'o}n and Trinidad and Rafael Ram{\'i}rez‐Camacho and Jos{\'e} Ram{\'o}n Garc{\'i}a-Berrocal},
  journal={Journal of Otolaryngology-ENT Research},
  year={2015},
  volume={3}
}
Objective: To evaluate the effectiveness and safety of Intratympanic methylprednisolone injection in patients with sudden sensorineural hearing loss (SSNHL) by means of a comparison between subjective and objective outcomes and a review of the literature regarding methylprednisolone transtympanic administration. Data Sources: An electronic database search (MEDLINE and PubMed) was performed with the objective of identifying all studies published in the English language between January 1980 and… 
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Citation Type

Role of Intratympanic Steroids in the Management of Idiopathic Sudden Sensori-Neural Hearing Loss
Efficacy of Intratympanic Corticosteroid as a Salvage Treatment in Idiopathic Sudden Sensorineural Hearing Loss
Update on consensus on diagnosis and treatment of idiopathic sudden sensorineural hearing loss
Can sudden sensorineural hearing loss predict stroke? A long-term study
TLDR
There seems to be a relationship between SHL and stroke, especially in patients with cardiovascular risk factors, and a longer follow-up is recommended since stroke may develop several years after the onset of the hearing loss episode.
Eficacia del corticoide intratimpánico como tratamiento de rescate en sordera súbita neurosensorial idiopática
Actualización del consenso sobre el diagnóstico y tratamiento de la sordera súbita idiopática

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TLDR
Intratympanic steroid treatment as primary treatment for sudden sensorineural hearing loss appears equivalent to treatment with high-dose oral prednisone therapy, and as salvage therapy, intratYmpanic steroids offer the potential for some degree of additional hearing recovery, although it remains uncertain if this improvement is clinically significant and what percentage of patients is likely to show benefit.
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Three intratympanic injections of methylprednisolone improved pure-tone average or speech discrimination scores for a subset of sudden hearing loss subjects that failed to benefit from oral steroids.
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Intratympanic Methylprednisolone Improves Hearing Function in Refractory Sudden Sensorineural Hearing Loss: A Control Study
TLDR
IT steroid therapy can improve hearing function in patients with SSNHL after the failure of systemic steroid treatment, and this treatment was significantly better than that in the other two groups.
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OBJECTIVE to evaluate the effectiveness of transtympanic methylprednisolone injection in patients with refractory sudden sensorineural hearing loss via endoscopic diode laser myringotomy. SUBJECTS…
Intratympanic Steroids for Idiopathic Sudden Sensorineural Hearing Loss
TLDR
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TLDR
Instillation of intratympanic steroids represents a safe and potentially effective treatment of sudden idiopathic sensorineural hearing loss and those treated within 10 days of onset had a statistically significant better outcome.
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