Intratympanic Gentamicin for Intractable Meniere's Disease

@article{Prez2003IntratympanicGF,
  title={Intratympanic Gentamicin for Intractable Meniere's Disease},
  author={Nicol{\'a}s P{\'e}rez and Eduardo Mart{\'i}n and Rafael Garc{\'i}a-Tapia},
  journal={The Laryngoscope},
  year={2003},
  volume={113}
}
Objective The study aimed to analyze the results of the intratympanic injection of gentamicin as a treatment option for patients with unilateral Meniere's disease who were refractory to medical treatment. 
Intratympanic Gentamicin for Menière's Disease: a Meta‐Analysis
TLDR
The published experience on intratympanic gentamicin treatment for intractable Menière's disease is reviewed to systematically review the published experience.
Management of intractable Ménière's disease after intratympanic injection of Gentamicin
1) To evaluate the efficacy of, and problems with, intratympanic gentamicin injection (ITG) in medically intractable definite Ménière's disease (MD) and secondary endolymphatic hydrops (EH); and 2)
Long‐Term Disability of Class A Patients With Ménière's Disease After Treatment With Intratympanic Gentamicin
TLDR
Patients with Ménière's disease who had achieved complete control of vertigo through intratympanic gentamicin treatment were characterized and the Functional Level Score prior to treatment reflected the posttreatment symptoms and disability.
Medical Management Of Ménière's Disease
TLDR
Ménière's disease is poorly understood with respect to its etiology, pathophysiology, clinical course, and treatment and in the absence of controlled clinical studies, empiric treatments have been used with varying degrees of success.
Intratympanic gentamicin in Ménière's disease: our experience
TLDR
This intratympanic gentamicin injection protocol enabled effective vertigo control in most patients, and represents a good alternative to more aggressive techniques for the treatment of Ménière's disease which does not respond to medical treatment.
Intratympanic / Transtympanic Gentamicin Treatment for Meniere ' s Disease
  • Medicine
  • 2018
TLDR
In severe cases of episodic vertigo, treatments that deaden the inner ear such as gentamicin injections may be considered, and this is usually a last resort treatment for persons who have severe attacks of vertigo.
Evaluation of Two Procedures of Intratympanic Gentamicin Therapy in Meniere ’ s Disease
The majority of patients with Meniere’s disease (MD) may be managed conservatively with medical therapy. Those who have symptoms refractory to medical management may benefit from surgery. Recently
Time course of repeated intratympanic gentamicin for ménière's disease
TLDR
The objective is to provide a description of the time course of recurrent vertigo and repeated injections with a Kaplan‐Meier survival analysis, which may enable accurate predictions of the probability of recurrent Vertigo after a given time or number of injections.
Medical and noninvasive therapy for Meniere's disease.
Intratympanic gentamicin therapy for intractable Ménière's disease
TLDR
Intratympanic Gentamicin treatment using a low dose of gentamicin applied at intervals of a minimum of 27 days, has been shown to be a successful treatment of vertigo.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 34 REFERENCES
Intratympanic Gentamicin for the Treatment of Unilateral Meniere's Disease
Objective To determine the efficacy of intratympanic gentamicin instillation as treatment of incapacitating unilateral Meniere's disease, using a predetermined regimen with a fixed dose.
Update on Intratympanic Gentamicin for Meniere's Disease
TLDR
The literature relating to intratympanic gentamicin injection therapy for Meniere's disease is reviewed to detect consistencies and differences that might suggest optimal technique.
Intratympanic gentamicin therapy for meniere’s disease
  • A. Bhattacharyya
  • Medicine
    Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • 1997
TLDR
Intratympanic Gentamicin for the treatment of Meniere's Disease has been tried as early as 1978 and is now back in vogue evidenced by the recent spate of articles in almost all international journals of otolaryngology.
Intratympanic gentamicin therapy for Menière's disease: preliminary comparison of two regimens.
TLDR
Results indicate that the weekly interval treatment of intratympanic gentamicin therapy offers equivalent efficacy with considerably less risk to hearing.
Intratympanic Gentamicin for Treatment of Intractable Meniere's Disease: A Preliminary Report
TLDR
Intratympanic gentamicin offers better risk/benefit outcome than other invasive therapies for intractable Meniere's disease.
[Intratympanic gentamicin in Menière's disease].
TLDR
Intratympanic gentamicin injection is a simple and cost-effective means for controlling intractable vertigo of Menière's disease, but it also has some toxic effect to hearing.
Intratympanic gentamicin titration therapy for intractable Meniere's disease.
TLDR
Intratympanic gentamicin titration therapy provides excellent vertigo control with a low incidence of hearing loss, and the group showed no combined statistically significant changes in any of the hearing parameters.
10 Years of experience with intratympanally applied streptomycin (gentamycin) in the therapy of Morbus Menière
TLDR
The proposed therapy was to administer streptomycin (gentamycinsulfate) intratympanically by applying two different ways of procedure and attempted to exclusively destroy the secretorial epithelium with minimal dosages of aminoclycosid antibiotics.
Intratympanic gentamicin in Ménière's disease: results of therapy.
TLDR
It is concluded and confirmed that intratympanic gentamicin injections are a convenient and, in most cases, effective and safe treatment for intractable vertigo or drop attacks due to Ménière's disease.
Intratympanic gentamicin for control of vertigo in Meniere's disease: vestibular signs that specify completion of therapy.
  • L. Minor
  • Medicine
    The American journal of otology
  • 1999
TLDR
Ending weekly intratympanic gentamicin injections when clinical signs of unilateral vestibular hypofunction appear can control vertigo in most patients.
...
1
2
3
4
...