Intratumoral tissue factor expression and risk of venous thromboembolism in brain tumor patients.

@article{Thaler2013IntratumoralTF,
  title={Intratumoral tissue factor expression and risk of venous thromboembolism in brain tumor patients.},
  author={Johannes Thaler and Matthias Preusser and Cihan Ay and Alexandra Kaider and Christine Marosi and Christoph Carl Zielinski and Prof. Dr. Ingrid Pabinger and Johannes Andreas Hainfellner},
  journal={Thrombosis research},
  year={2013},
  volume={131 2},
  pages={
          162-5
        }
}
BACKGROUND Brain tumor patients have an increased risk of venous thromboembolism (VTE). An important role in cancer-related VTE has been suggested for tissue factor (TF), the main initiator of the coagulation cascade. We conducted a prospective cohort study to determine whether expression levels of TF in brain tumors are associated with future VTE. PATIENTS AND METHODS We immunohistochemically determined TF-expression in brain tumor specimens of 96 adult patients (8 low-grade and 82 high… CONTINUE READING
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