Intratumoral tertiary lymphoid organ is a favourable prognosticator in patients with pancreatic cancer

@inproceedings{Hiraoka2015IntratumoralTL,
  title={Intratumoral tertiary lymphoid organ is a favourable prognosticator in patients with pancreatic cancer},
  author={Nobuyoshi Hiraoka and Yoshinori Ino and Rie Yamazaki-Itoh and Yae Kanai and Tomoo Kosuge and Kazuaki Shimada},
  booktitle={British Journal of Cancer},
  year={2015}
}
Background:Host immunity has critical roles in tumour surveillance. Tertiary lymphoid organs (TLOs) are induced in various inflamed tissues. The aim of this study was to investigate the clinicopathological and pathobiological characteristics of tumour microenvironment in pancreatic ductal carcinoma (PDC) with TLOs.Methods:We examined 534 PDCs to investigate the clinicopathological impact of TLOs and their association with tumour-infiltrating immune cells, the cytokine milieu, and tissue… CONTINUE READING
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