Intratumoral lymphocyte density in serous ovarian carcinoma is superior to ERCC1 expression for predicting response to platinum-based therapy

@article{Bsmller2011IntratumoralLD,
  title={Intratumoral lymphocyte density in serous ovarian carcinoma is superior to ERCC1 expression for predicting response to platinum-based therapy},
  author={Hans C B{\"o}sm{\"u}ller and Sophie Haitchi-Petnehazy and Gerald Webersinke and Renate Marschon and Franz Roithmeier and Wolfgang Stummvoll and Tanja Fehm and Margit Klier-Richter and Irina Bonzheim and Annette Staebler and Falko Fend},
  journal={Virchows Archiv},
  year={2011},
  volume={459},
  pages={183-191}
}
Intratumoral immune cells and ERCC1 expression are likely to play a role in the response of ovarian carcinoma to chemotherapy, but their impact on therapy outcome is still unclear. Therefore, 41 cases of optimally resected high grade serous ovarian carcinomas were examined retrospectively for stromal and intraepithelial lymphocyte populations and ERCC1 status in relation to response to platinum-based therapy. Based on RECIST criteria, 27 patients were classified as responsive and 14 as therapy… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 13 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 39 REFERENCES

Prediction of response to chemotherapy by ERCC1 immunohistochemistry and ERCC1 polymorphism in ovarian cancer

  • KD Steffensen, M Waldstrom, U Jeppesen, I Brandslund, A Jakobson
  • Int J Gynecol Cancer
  • 2008
Highly Influential
7 Excerpts

Similar Papers

Loading similar papers…