Intratumoral delivery of mitoxantrone in association with 90-Y radioimmunotherapy (RIT) in recurrent glioblastoma

@article{Boiardi2004IntratumoralDO,
  title={Intratumoral delivery of mitoxantrone in association with 90-Y radioimmunotherapy (RIT) in recurrent glioblastoma},
  author={Amerigo Boiardi and Mirco Bartolomei and Antonio Silvani and Marica Eoli and Andrea Salmaggi and Elena A. Lamperti and Ida Maddalena Milanesi and Andrea Botturi and Paola Della Rocca and Lisa Bodei and Giovanni Broggi and Giovanni Paganelli},
  journal={Journal of Neuro-Oncology},
  year={2004},
  volume={72},
  pages={125-131}
}
Twenty-six recurrent Glioblastoma (rGBM) patients sequentially treated at the National Neurological Institute ‘C Besta’ were enrolled for a second surgery in order to remove recurrent tumor and to place an Ommaya reservoire to allow local delivery of chemotherapy and local pre-targeted radio-immunotherapy (RIT). All patients had partial tumor resection and 75% of them had a residual tumor mass after exeresis larger than 2 cm. After surgery all patients were managed with a second line systemic… CONTINUE READING
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