Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer.

@article{Zhang2003IntratumoralTC,
  title={Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer.},
  author={Lin Zhang and Jose R. Conejo-Garcia and Dionyssios Katsaros and Phyllis A. Gimotty and Marco Massobrio and Giorgia Regnani and Antonis Makrigiannakis and Heidi J. Gray and Katia Schlienger and Michael N. Liebman and Stephen C. Rubin and George Coukos},
  journal={The New England journal of medicine},
  year={2003},
  volume={348 3},
  pages={
          203-13
        }
}
BACKGROUND Although tumor-infiltrating T cells have been documented in ovarian carcinoma, a clear association with clinical outcome has not been established. METHODS We performed immunohistochemical analysis of 186 frozen specimens from advanced-stage ovarian carcinomas to assess the distribution of tumor-infiltrating T cells and conducted outcome analyses. Molecular analyses were performed in some tumors by real-time polymerase chain reaction. RESULTS CD3+ tumor-infiltrating T cells were… 

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