Intratumoral α-SMA Enhances the Prognostic Potency of CD34 Associated with Maintenance of Microvessel Integrity in Hepatocellular Carcinoma and Pancreatic Cancer

@inproceedings{Wang2013IntratumoralE,
  title={Intratumoral α-SMA Enhances the Prognostic Potency of CD34 Associated with Maintenance of Microvessel Integrity in Hepatocellular Carcinoma and Pancreatic Cancer},
  author={Wen Wang and Liang Liu and Hua-Xiang Xu and Guo-pei Luo and Tao Chen and Chun-tao Wu and Yongfeng Xu and Jin Xu and Chen Liu and Bo Zhang and Jiang Long and Zhao-you Tang and Xianjun Yu},
  booktitle={PloS one},
  year={2013}
}
Microvessel density (MVD) as an angiogenesis predictor is inefficient per se in cancer prognosis. We evaluated prognostic values of combining intratumoral alpha-smooth muscle actin (α-SMA)-positive stromal cell density and MVD after curative resection in hypervascular hepatocellular carcinoma (HCC) and hypovascular pancreatic cancer (PC). Tissue microarrays were constructed from tumors of 305 HCC and 57 PC patients who underwent curative resection and analyzed for α-SMA and CD34 expression by… CONTINUE READING