Intrathecal morphine suppresses NK cell activity following abdominal surgery.

@article{Yokota2000IntrathecalMS,
  title={Intrathecal morphine suppresses NK cell activity following abdominal surgery.},
  author={Tetsuya Yokota and Kiyoshi Uehara and Yukiko Nomoto},
  journal={Canadian journal of anaesthesia = Journal canadien d'anesthesie},
  year={2000},
  volume={47 4},
  pages={303-8}
}
PURPOSE The effects of morphine on natural killer (NK) cell activity were investigated in patients who underwent hysterectomy. METHODS Forty patients were divided into four groups of ten. The groups received intrathecal 0.5 mg morphine (Group IT0.5), intrathecal 0.1 mg morphine (Group IT0.1) or 10 mg morphine i.v. (Group IV). The remaining ten patients served as controls and received inhalation anesthesia alone (Group C). Blood samples were withdrawn before and two hours after surgery and on… CONTINUE READING