Intrathecal lemnalol, a natural marine compound obtained from Formosan soft coral, attenuates nociceptive responses and the activity of spinal glial cells in neuropathic rats

@article{Lin2011IntrathecalLA,
  title={Intrathecal lemnalol, a natural marine compound obtained from Formosan soft coral, attenuates nociceptive responses and the activity of spinal glial cells in neuropathic rats},
  author={Ying-Chao Lin and Shi-Ying Huang and Yen-Hsuan Jean and Wu-Fu Chen and C. Sung and Erl-Shyh Kao and H. Wang and C. Chakraborty and C. Duh and Zhi-Hong Wen},
  journal={Behavioural Pharmacology},
  year={2011},
  volume={22},
  pages={739–750}
}
  • Ying-Chao Lin, Shi-Ying Huang, +7 authors Zhi-Hong Wen
  • Published 2011
  • Psychology, Medicine
  • Behavioural Pharmacology
  • The investigators previously found that the administration of lemnalol, a natural marine compound isolated from the Formosan soft coral Lemnalia cervicorni, produced anti-inflammatory and analgesic effects in carrageenan-injected rats. Recently, several studies have demonstrated that the development and maintenance of neuropathic pain are accompanied by releasing of proinflammatory mediators from activated glial cells in the spinal cord. In this study, we investigated the antinociceptive… CONTINUE READING
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