Intrathecal baclofen in X-linked adrenoleukodystrophy.

  title={Intrathecal baclofen in X-linked adrenoleukodystrophy.},
  author={Mary Lynn Chu and Debra A. Sala and Howard L. Weiner},
  journal={Pediatric neurology},
  volume={24 2},
X-linked adrenoleukodystrophy is a progressive neurodegenerative disorder involving the destruction of white matter in the brain and adrenocortical hormone deficiency. Clinical symptoms first appear between 4 and 8 years of age and include spasticity, visual loss, dysphagia, and seizures. In this report, continuous infusion of intrathecal baclofen was used to treat the severe spasticity of an 8-year-old patient with X-linked adrenoleukodystrophy. The improvement in this patient's quality of… CONTINUE READING


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