Intrathecal baclofen for the treatment of dystonia in patients with reflex sympathetic dystrophy.

@article{Hilten2000IntrathecalBF,
  title={Intrathecal baclofen for the treatment of dystonia in patients with reflex sympathetic dystrophy.},
  author={Bob JJ van Hilten and Willem-Johan T van de Beek and Jorrit I. Hoff and Joan H. C. Voormolen and Elmar M. Delhaas},
  journal={The New England journal of medicine},
  year={2000},
  volume={343 9},
  pages={
          625-30
        }
}
BACKGROUND AND METHODS Patients with reflex sympathetic dystrophy (also known as the complex regional pain syndrome) may have dystonia, which is often unresponsive to treatment. Some forms of dystonia respond to the intrathecal administration of baclofen, a specific gamma-aminobutyric acid-receptor (type B) agonist that inhibits sensory input to the neurons of the spinal cord. We evaluated this treatment in seven women who had reflex sympathetic dystrophy with multifocal or generalized tonic… CONTINUE READING
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