Intrathecal antibody production against Epstein-Barr and other neurotropic viruses in pediatric and adult onset multiple sclerosis

@inproceedings{Pohl2009IntrathecalAP,
  title={Intrathecal antibody production against Epstein-Barr and other neurotropic viruses in pediatric and adult onset multiple sclerosis},
  author={Daniela Pohl and Kevin Rost{\'a}sy and Christian Jacobi and Peter de Lange and Roland Nau and Bernd Krone and Folker A Hanefeld},
  booktitle={Journal of Neurology},
  year={2009}
}
Epstein-Barr virus (EBV) has been implicated in the pathogenesis of multiple sclerosis (MS). Recent reports proposed an increased EBV-targeted humoral immune response in MS, which appears to be more pronounced in pediatric patients. However, little is known about the CNS-derived antibody production against EBV in patients with MS. The objective of this study was to assess the frequency and intensity of intrathecal antibody production against EBV as compared to other neurotropic viruses in… CONTINUE READING
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