Intratesticular transplantation of testicular cells from leukemic rats causes transmission of leukemia.

@article{Jahnukainen2001IntratesticularTO,
  title={Intratesticular transplantation of testicular cells from leukemic rats causes transmission of leukemia.},
  author={Kirsi Jahnukainen and Mi Hou and Cecilia Petersen and Brian P. Setchell and Olle S{\"o}der},
  journal={Cancer research},
  year={2001},
  volume={61 2},
  pages={706-10}
}
A rat T-cell leukemia model was used to study the safety of germ cell transplantation as a mean of preventing infertility in males undergoing gonadotoxic cancer treatment. Donor germ cells were harvested from the testes of terminally ill leukemic rats and were either used directly or cryopreserved and thawed before transplantation by rete testis microinjection. All rats transplanted with testicular cells from leukemic donors developed signs of terminal rat T-cell leukemia, whereas control… CONTINUE READING
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