Intrasphincteric botulinum toxin injection in the treatment of chagasic achalasia.

  title={Intrasphincteric botulinum toxin injection in the treatment of chagasic achalasia.},
  author={C{\'e}sar Q Brant and Joaquim Prado Pinto de Moraes-Filho and Eduardo Sampaio Siqueira and Ary Nasi and Ermelindo Della L{\'i}bera and Marta C. Morais and Michael Rohr and Erika Pereira de Macedo and Guillermo Alonso and {\^A}ngelo Paulo Ferrari},
  journal={Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus},
  volume={16 1},
According to the WHO, 16-18 million people in Central and South America are infected by Trypanosoma cruzi. Chagasic achalasia affects between 7.1% and 10.6% of the population. The aim of this study was to evaluate the effects of Botox injections in the clinical response and esophageal function of patients with dysphagia due to chagasic achalasia. In total, 24 symptomatic patients with chagasic achalasia were randomly chosen to receive Botulinum Toxin (BT) or saline injected by endoscopy in the… CONTINUE READING