Intrarenal renin-angiotensin system and counteracting protective mechanisms in angiotensin II-dependent hypertension.

@article{Mitchell2007IntrarenalRS,
  title={Intrarenal renin-angiotensin system and counteracting protective mechanisms in angiotensin II-dependent hypertension.},
  author={Kenneth D. Mitchell and Fady T. Botros and Luis Gabriel Navar},
  journal={Acta physiologica Hungarica},
  year={2007},
  volume={94 1-2},
  pages={31-48}
}
It is now well accepted that alterations in kidney function, due either to primary renal disease or to inappropriate hormonal influences on the kidney, are a cardinal characteristic in all forms of hypertension, and lead to a reduced ability of the kidneys to excrete sodium and the consequent development of elevated arterial pressures. However, it is also… CONTINUE READING