Intrarenal renin, angiotensin II, and plasma renin in rats with uranyl nitrate-induced and glycerol-induced acute renal failure.

@article{Mendelsohn1980IntrarenalRA,
  title={Intrarenal renin, angiotensin II, and plasma renin in rats with uranyl nitrate-induced and glycerol-induced acute renal failure.},
  author={F. Mendelsohn and E. Smith},
  journal={Kidney international},
  year={1980},
  volume={17 4},
  pages={
          465-72
        }
}
Intrarenal renin, angiotensin II, and plasma renin in rats with uranyl nitrate-induced and glycerol-induced acute renal failure. Uranyl nitrate (UN) (10 mg/kg body wt, i.p.) produced acute polyuric renal failure (ARF) in rats. Six and 18 hours after UN administration, the animals had elevated urine flow rates and sodium excretion, raised plasma creatinine concentrations, and impaired endogenous creatinine clearance. At this time, intrarenal angiotensin II (AII) was markedly elevated as was… Expand
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