Intrarenal localization of the natriuretic effect of cardiac atrial extract.

@article{Sonnenberg1982IntrarenalLO,
  title={Intrarenal localization of the natriuretic effect of cardiac atrial extract.},
  author={Harald Sonnenberg and William A. Cupples and Adolfo J. de Bold and Anthony T. Veress},
  journal={Canadian journal of physiology and pharmacology},
  year={1982},
  volume={60 9},
  pages={1149-52}
}
In anesthetized rats micropuncture and microcatheterization were used to collect tubular fluid from end proximal and distal tubules and from the outer medullary collecting duct. Urine was collected at the papilla tip. Samples were taken from the same sites before and after intravenous injection of atrial tissue extract; rats injected with ventricular extract served as controls. Sodium excretion increased 17-fold after atrial extract, a significantly greater rise than the 3-fold increase after… CONTINUE READING