Intrapulmonary aquaporin-5 expression as a possible biomarker for discriminating smothering and choking from sudden cardiac death: a pilot study.

@article{Wang2012IntrapulmonaryAE,
  title={Intrapulmonary aquaporin-5 expression as a possible biomarker for discriminating smothering and choking from sudden cardiac death: a pilot study.},
  author={Qi Wang and Takaki Ishikawa and Tomomi Michiue and Baoli Zhu and Da-wei Guan and Hitoshi Maeda},
  journal={Forensic science international},
  year={2012},
  volume={220 1-3},
  pages={
          154-7
        }
}
The diagnosis of mechanical asphyxia as a cause of death, especially smothering and choking lacking evident injury, is one of the most difficult tasks in forensic pathology. The present study investigated the intrapulmonary expressions of aquaporins (AQPs; AQP-1 and AQP-5), as markers of water homeostasis, in forensic autopsy cases (total n=64, within 48 h postmortem) of mechanical asphyxiation due to neck compression (strangulation, n=24), including manual/ligature strangulation (n=12) and… CONTINUE READING

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