Intraperitoneal verapamil therapy in CAPD patients with peritoneal hypopermeability. Effects on ultrafiltration.

@article{Lamperi1988IntraperitonealVT,
  title={Intraperitoneal verapamil therapy in CAPD patients with peritoneal hypopermeability. Effects on ultrafiltration.},
  author={S Lamperi and Silvia Carozzi and Maria Grazia Nasini and Marco Canepa and Tina Zanin},
  journal={ASAIO transactions},
  year={1988},
  volume={34 3},
  pages={425-8}
}
We found higher peritoneal lymphocyte (PLy) and macrophage (PM0) Ca++ concentrations in CAPD patients with low peritoneal ultrafiltration (UF), than in normal UF patients, as well as the release of greater amounts of lymphomonokines such as interferon-gamma and interleukin-1, which stimulate peritoneal fibroblast proliferation. Since Ca++ is essential in immune-cell activation and lymphomonokine production, the authors analyzed the effects of intraperitoneal (IP) verapamil therapy in 16 CAPD… CONTINUE READING

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