Intraperitoneal heparin ameliorates the systemic inflammatory response in PD patients.

  title={Intraperitoneal heparin ameliorates the systemic inflammatory response in PD patients.},
  author={Jonas Angel Sj\oland and R. J. S. Pedersen and J\orgen Jespersen and J\orgen Gram},
  journal={Nephron. Clinical practice},
  volume={100 4},
BACKGROUND Patients with end-stage renal disease (ESRD) suffer from high mortality rates of cardiovascular diseases, conditions closely linked to the magnitude of their chronic low-grade inflammation. As heparins have been suggested to possess anti-inflammatory properties, we set out to investigate the impact of long-term treatment with intraperitoneal heparin on local and systemic inflammation in peritoneal dialysis (PD) patients. METHODS In a double-blinded cross-over study, 21 PD patients… CONTINUE READING


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