Intrapatient variations in type 1 diabetes-specific iPS cell differentiation into insulin-producing cells.

@article{Thatava2013IntrapatientVI,
  title={Intrapatient variations in type 1 diabetes-specific iPS cell differentiation into insulin-producing cells.},
  author={Tayaramma Thatava and Yogish C. Kudva and Ramakrishna Edukulla and Karen A. Squillace and Josep Genebriera De Lamo and Yulia Krotova Khan and Toshie Sakuma and Seiga Ohmine and Andre Terzic and Yasuhiro Ikeda},
  journal={Molecular therapy : the journal of the American Society of Gene Therapy},
  year={2013},
  volume={21 1},
  pages={228-39}
}
Nuclear reprogramming of adult somatic tissue enables embryo-independent generation of autologous, patient-specific induced pluripotent stem (iPS) cells. Exploiting this emergent regenerative platform for individualized medicine applications requires the establishment of bioequivalence criteria across derived pluripotent lines and lineage-specified derivatives. Here, from individual patients with type 1 diabetes (T1D) multiple human iPS clones were produced and prospectively screened using a… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

Recent Advances in Stem Cells

Stem Cell Biology and Regenerative Medicine • 2016
View 4 Excerpts
Highly Influenced

Non-coding genome functions in diabetes.

Journal of molecular endocrinology • 2016
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 58 references

Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy.

Proceedings of the National Academy of Sciences of the United States of America • 2011

Similar Papers

Loading similar papers…