Intrapartal cardiotocographic patterns and hypoxia-related perinatal outcomes in pregnancies complicated by gestational diabetes mellitus

  title={Intrapartal cardiotocographic patterns and hypoxia-related perinatal outcomes in pregnancies complicated by gestational diabetes mellitus},
  author={Mikko Tarvonen and Petteri Hovi and Susanna Sainio and Piia Vuorela and Sture Andersson and Kari Teramo},
  journal={Acta Diabetologica},
  pages={1563 - 1573}
In previous reports, cardiotocographic (CTG) fetal heart rate (FHR) monitoring has shown only limited benefits in decreasing adverse perinatal outcomes in pregnancies complicated by gestational diabetes mellitus (GDM). The aim of the present study was to evaluate whether an association exists between the recently reported ZigZag pattern (FHR baseline amplitude changes of > 25 bpm with a duration of 2–30 min) and asphyxia-related neonatal outcomes in GDM pregnancies. Intrapartal CTGs were… 
3 Citations
The birth of cardiac disease: Mechanisms linking gestational diabetes mellitus and early onset of cardiovascular disease in offspring.
Evidence linking GDM and CVD development in the offspring is gathered, providing new insights on novel mechanisms contributing to offspring CVD programming by GDM, from the role of maternal-fetal interactions to their impact on fetal cardiovascular development.
Immunoendocrine Dysregulation during Gestational Diabetes Mellitus: The Central Role of the Placenta
The placenta is focused on as an immuno-endocrine organ that can recognize and respond to the hyperglycemic environment and play a role in inflammation, innate defense, endocrine response, oxidative stress, and angiogenesis, all associated with different perinatal outcomes.
Prenatal Hypoxia Affects Foetal Cardiovascular Regulatory Mechanisms in a Sex- and Circadian-Dependent Manner: A Review
Even short-term prenatal hypoxia significantly affects cardiovascular regulatory mechanisms and programs hypertension in adulthood, while prenatal programming effects are not only dependent on the critical period, and sensitivity can change within circadian oscillations.


Saltatory Pattern of Fetal Heart Rate during Labor Is a Sign of Fetal Hypoxia
Saltatory pattern in an intrapartum FHR recording is an early sign of fetal hypoxia during the last 2 h of labor.
Peripartum fetal distress in diabetic women: a retrospective case-cohort study
Women with type 1 and type 2 diabetes are at increased risk of fetal distress during labor as compared to controls.
Intrapartum cardiotocography (CTG) and ST-analysis of labor in diabetic patients
A preterminal CTG is more common in the fetuses of DM than GD mothers during labor, and when CTG was normal at the start of recording, the addition of FECG information gave a significant add on information to predict moderate acidemia.
Continuous cardiotocography during labour: Analysis, classification and management.
Detection of pregnancies with high risk of fetal macrosomia among women with gestational diabetes mellitus
The 24‐hour glucose profile performed after the diagnosis of GDM clearly distinguishes between low‐risk (diet‐treated) and high‐ risk (insulin‐ treated) for fetal macrosomia in GDM pregnancies.
Placental pathologic changes in gestational diabetes mellitus.
Changes of the development, anatomy and function of the placenta in the environment of abnormal glucose metabolism which can establish the maternal-placental-fetal interface dysfunction as a potential source of adverse pregnancy outcomes are reviewed.
Continuous intrapartum fetal monitoring in gestational diabetes, where is the evidence?
  • Salma Jabak, A. Hameed
  • Medicine
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
  • 2020
There is an urgent need to conduct randomized controlled trials on women with well-controlled GDM and normal fetal growth scans so that these women could be provided evidence-based information on their options of birth.
Increased Neonatal Respiratory Morbidity Associated with Gestational and Pregestational Diabetes: A Retrospective Study
G gestational and pregestational diabetes were associated with increased risks of neonatal respiratory morbidity compared with women without diabetes regardless of probability to deliver at term and diabetes was associated withincreased risk of neonatic respiratory morbidities beyond what can be attributed to prematurity.