Intrapancreatic schwannoma diagnosed by endoscopic ultrasound-guided fine-needle aspiration cytology.


Schwannoma is a tumor of neuro-ectodermal origin, usually occuring in the head and neck and extremities. A retroperitoneal, and particularly intra-pancreatic presentation is very rare, and poses a clinical and diagnostic challenge. We report a case of a male patient who underwent an Endoscopic Ultrasound-guided Fine Needle Aspiration (EUS-FNA) biopsy of a hypoechoic, intra-pancreatic mass. The onsite cytological evaluation was consistent with a spindle cell neoplasm. Further evaluation, aided by immunohistochemical stains, defined the mass as a Schwannoma. The patient then underwent a pancreaticoduodenectomy and the histopathological diagnosis of the surgical specimen confirmed the cytological diagnosis. To our knowledge, this is the first report of intra-pancreatic Schwannoma diagnosed preoperatively by EUS-FNA cytology.

DOI: 10.1002/dc.20985
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@article{Li2009IntrapancreaticSD, title={Intrapancreatic schwannoma diagnosed by endoscopic ultrasound-guided fine-needle aspiration cytology.}, author={Shaoying Li and Syed Z Ai and Christopher Owens and Peter Kulesza}, journal={Diagnostic cytopathology}, year={2009}, volume={37 2}, pages={132-5} }