Intraoperative small-dose ketamine enhances analgesia after outpatient knee arthroscopy.

  title={Intraoperative small-dose ketamine enhances analgesia after outpatient knee arthroscopy.},
  author={Christophe M{\'e}nigaux and Bruno Guignard and Dominique Fletcher and Daniel I Sessler and X Dupont and Marcel Chauvin},
  journal={Anesthesia and analgesia},
  volume={93 3},
Ketamine may prevent postoperative hyperalgesia. In patients undergoing arthroscopic meniscectomy using general anesthesia, we tested whether a single intraoperative dose of ketamine enhanced postoperative analgesia and improved functional outcome compared with a typical multimodal analgesic regimen. After the induction of anesthesia, 50 patients were randomly assigned to ketamine (0.15 mg/kg IV just after the induction of anesthesia) or a vehicle placebo. Standardized general anesthesia… CONTINUE READING
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