Intraoperative radiotherapy in the combination of adjuvant chemotherapy for the treatment of pT3N0M0 rectal cancer after radical surgery.

Abstract

OBJECTIVES The role of chemoradiotherapy in patients with pT3N0M0 rectal cancer is controversial. Intraoperative radiotherapy (IORT) has the ability to deliver a high, single-fraction radiation dose to tumor bed with minimal exposure of surrounding tissues. On the basis of the literature, the local failure pattern occurs mostly in the presacral-perineal… (More)
DOI: 10.1097/COC.0b013e31825eb75c

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