Intraoperative radioimmunolocalization of an anti-CEA MAb F(Ab')2 (FO23C5) in CEA serum-negative colorectal cancer patients.

@article{Roselli1996IntraoperativeRO,
  title={Intraoperative radioimmunolocalization of an anti-CEA MAb F(Ab')2 (FO23C5) in CEA serum-negative colorectal cancer patients.},
  author={Mario Roselli and Fiorella Guadagni and Oreste Claudio Buonomo and Augusto Belardi and Valeria Vittorini and Andrea Cavazzana and Luigi Giusto Spagnoli and Cesidio Cipriani and Carlo Umberto Casciani},
  journal={Anticancer research},
  year={1996},
  volume={16 2},
  pages={883-9}
}
Serum positivity to an antigen recognized by the monoclonal antibody (MAb) which will be administered is frequently being used as a predictive criterion for positive MAb tumor localization. In the present study, which is based on our previous data that clearly showed no correlation between quantitative levels of CEA in sera and in carcinoma tissues, we selected a population of 12 primary colorectal carcinoma patients which were serum CEA-negative. The main purpose was to assess the potential… CONTINUE READING

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