Intraoperative radiation therapy for malignant glioma.

  title={Intraoperative radiation therapy for malignant glioma.},
  author={Naoto Sakai and Hidehisa Yamada and Takashi Andoh and Takeo Hirata and Yuusuke Nishimura and Yoshiji Miwa and Kazuhiko Shimizu and Shigeo Yanagawa},
  journal={Neurologia medico-chirurgica},
  volume={31 11},
Intraoperative radiation therapy (IORT) was used as part of the initial therapy for malignant glioma in 32 of 73 patients with histologically verified anaplastic astrocytoma (grade III astrocytoma) and glioblastoma multiforme. The initial treatment for all cases was subtotal or total tumor resection combined with external irradiation and chemotherapy. IORT was performed 1 week after tumor resection, with doses of 10-50 Gy (mean 26.7 Gy) in one session. Fourteen of 32 cases had IORT two times… CONTINUE READING


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