Intraoperative embolus formation during cardiopulmonary bypass affects the release of S100B.

@article{BabinEbell1999IntraoperativeEF,
  title={Intraoperative embolus formation during cardiopulmonary bypass affects the release of S100B.},
  author={Joerg Babin-Ebell and M R Misoph and Wolfgang Muellges and Konrad Neukam and Jeffrey Reese and Olaf Elert},
  journal={The Thoracic and cardiovascular surgeon},
  year={1999},
  volume={47 3},
  pages={166-9}
}
BACKGROUND Intraoperative thromboembolism and the systemic inflammatory reaction are thought to play a role in causing cerebral dysfunction following cardiopulmonary bypass (CPB). Increased levels of S100B, an astroglial protein, have been linked to neuropsychological deficits after CPB. The present study investigated whether S100B release correlates with intraoperative embolus formation, thrombin formation, or the release of inflammatory parameters. METHODS 40 patients undergoing coronary… CONTINUE READING