Intraoperative defect in haemostasis in a child receiving valproic acid.

@article{Tetzlaff1991IntraoperativeDI,
  title={Intraoperative defect in haemostasis in a child receiving valproic acid.},
  author={John E. Tetzlaff},
  journal={Canadian journal of anaesthesia = Journal canadien d'anesthesie},
  year={1991},
  volume={38 2},
  pages={222-4}
}
This report describes the development of an intraoperative defect in haemostasis which occurred during surgery for lengthening of the heel cords and release of hip contractures in a patient receiving valproic acid. A review of the literature failed to find any other cases of a valproic acid-induced bleeding disorder occurring under anaesthesia and surgery. While recognized in the non-surgical literature, this case reports the first in which the development of a valproic acid-induced haemostatic… CONTINUE READING