Intraocular pressure response to the replacement of pilocarpine or carbachol with echothiophate

  title={Intraocular pressure response to the replacement of pilocarpine or carbachol with echothiophate},
  author={Richard W. Reichert and Milton Bruce Shields},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
In 20 patients with open-angle glaucoma in aphakia or pseudophakia whose intraocular pressure had remained uncontrolled on their current medical therapy, the medication was changed from pilocarpine or carbachol to echothiophate iodide. In all, 12 patients (60%) showed a statistically significant improvement in pressure control, 7 (35%) showed no change, and 1 had higher pressure. One-third of the patients with improved intraocular-pressure control eventually required laser or incisional surgery… Expand
5 Citations
Lowering of IOP by Echothiophate Iodide in Pseudophakic Eyes with Glaucoma
EI substantially decreased the intraocular pressure (IOP) in pseudophakic glaucoma eyes receiving maximal medical therapy, including the newer class of medications, i.e., prostaglandin analogs, alpha-2 agonists, and topical carbonic anhydrase inhibitors. Expand
Intraocular pressure control with echothiophate iodide in children's eyes with glaucoma after cataract extraction.
  • C. Kraus, R. Trivedi, M. E. Wilson
  • Medicine
  • Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
  • 2015
EI lowered intraocular pressure to within an acceptable range with no significant adverse events, and in several patients it was the only pharmacologic agent that was successful in the control of glaucoma. Expand
Etude structurale de l'inhibition des cholinestérases par les neurotoxiques organophosphorés : stratégie de réactivation
Les pesticides et toxiques de guerre organophosphores sont responsables d'intoxications qui se revelent preoccupantes pour les autorites sanitaires. La recherche de solutions therapeutiques pourExpand


Dose-response analysis of echothiophate iodide.
  • L. Harris
  • Medicine
  • Archives of ophthalmology
  • 1971
The responses of intraocular pressure and outflow facility to echothiophate iodide concentrations from 0.03% to 0.25% were studied in open-angle glaucomatous patients, finding little rationale for the use of this drug in high concentration. Expand
Retinal detachment and miotic therapy.
The data suggest that detachment-prone eyes may be at increased risk with miotic use, and thus demand careful retinal evaluation and prophylaxis when ominous peripheral symptoms are present. Expand
Retinal detachments and topical ocular miotics.
Data supporting a possible cause and effect relationship, obtained from the National Registry of Drug-Induced Ocular Side Effects, a survey of the Retina Society, medicolegal decisions, and a review of the literature are presented. Expand
Retinal detachment and miotic thera
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  • 1978
[Miotics and retinal detachment (author's transl)].
  • P. Heinrich
  • Medicine
  • Klinische Monatsblatter fur Augenheilkunde
  • 1973
Comparison of pilocarpine and echothiophate iodide in open-angle glaucoma.