Intraocular distribution of intravitreally administered amphotericin B in normal and vitrectomized eyes.

@article{Wingard1989IntraocularDO,
  title={Intraocular distribution of intravitreally administered amphotericin B in normal and vitrectomized eyes.},
  author={Lemuel B. Wingard and J J Zuravleff and Bernard H Doft and Lee Berk and J S Rinkoff},
  journal={Investigative ophthalmology & visual science},
  year={1989},
  volume={30 10},
  pages={2184-9}
}
A study was performed to determine how amphotericin B is distributed in the eye after direct intravitreal injection. Radiolabeled amphotericin B was administered by direct injection into the vitreous space of unmodified phakic control or vitrectomized aphakic eyes in the rabbit model. The eyes were removed at different post-injection times, frozen and dissected into anatomical subparts of cornea, aqueous, iris, lens, vitreous and sclera-choroid-retina. The parts were assayed for total… CONTINUE READING

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Mentioned Connections BETA
ChoroidSibling in part ofRetina
However , progressive accumulation of radioactivity was observed in the sclera - choroid - retina tissue in the unmodified phakic eyes .
The eyes were removed at different post - injection times , frozen and dissected into anatomical subparts of cornea , aqueous , iris , lens , vitreous and sclera - choroid - retina .
RetinaSibling in part ofChoroid
The eyes were removed at different post - injection times , frozen and dissected into anatomical subparts of cornea , aqueous , iris , lens , vitreous and sclera - choroid - retina .
However , progressive accumulation of radioactivity was observed in the sclera - choroid - retina tissue in the unmodified phakic eyes .
ChoroidSibling in part ofSclera
However , progressive accumulation of radioactivity was observed in the sclera - choroid - retina tissue in the unmodified phakic eyes .
The eyes were removed at different post - injection times , frozen and dissected into anatomical subparts of cornea , aqueous , iris , lens , vitreous and sclera - choroid - retina .
ScleraSibling in part ofChoroid
The eyes were removed at different post - injection times , frozen and dissected into anatomical subparts of cornea , aqueous , iris , lens , vitreous and sclera - choroid - retina .
However , progressive accumulation of radioactivity was observed in the sclera - choroid - retina tissue in the unmodified phakic eyes .
EyeNo subtypeChoroid
However , progressive accumulation of radioactivity was observed in the sclera - choroid - retina tissue in the unmodified phakic eyes .
The eyes were removed at different post - injection times , frozen and dissected into anatomical subparts of cornea , aqueous , iris , lens , vitreous and sclera - choroid - retina .
EyeNo subtypeRetina
However , progressive accumulation of radioactivity was observed in the sclera - choroid - retina tissue in the unmodified phakic eyes .
The eyes were removed at different post - injection times , frozen and dissected into anatomical subparts of cornea , aqueous , iris , lens , vitreous and sclera - choroid - retina .
EyeNo subtypeSclera
However , progressive accumulation of radioactivity was observed in the sclera - choroid - retina tissue in the unmodified phakic eyes .
The eyes were removed at different post - injection times , frozen and dissected into anatomical subparts of cornea , aqueous , iris , lens , vitreous and sclera - choroid - retina .
EyeIs primary anatomic site of diseaseChoroidal hemangioma
The eyes were removed at different post - injection times , frozen and dissected into anatomical subparts of cornea , aqueous , iris , lens , vitreous and sclera - choroid - retina .
EyeIs associated anatomic site ofChoroidal hemangioma
The eyes were removed at different post - injection times , frozen and dissected into anatomical subparts of cornea , aqueous , iris , lens , vitreous and sclera - choroid - retina .
RetinaNo subtypeEye
The eyes were removed at different post - injection times , frozen and dissected into anatomical subparts of cornea , aqueous , iris , lens , vitreous and sclera - choroid - retina .
However , progressive accumulation of radioactivity was observed in the sclera - choroid - retina tissue in the unmodified phakic eyes .
RetinaAnatomic structure is physical part ofEye
The eyes were removed at different post - injection times , frozen and dissected into anatomical subparts of cornea , aqueous , iris , lens , vitreous and sclera - choroid - retina .
However , progressive accumulation of radioactivity was observed in the sclera - choroid - retina tissue in the unmodified phakic eyes .
RetinaNo subtypeSclera
The eyes were removed at different post - injection times , frozen and dissected into anatomical subparts of cornea , aqueous , iris , lens , vitreous and sclera - choroid - retina .
However , progressive accumulation of radioactivity was observed in the sclera - choroid - retina tissue in the unmodified phakic eyes .
ScleraNo subtypeRetina
The eyes were removed at different post - injection times , frozen and dissected into anatomical subparts of cornea , aqueous , iris , lens , vitreous and sclera - choroid - retina .
However , progressive accumulation of radioactivity was observed in the sclera - choroid - retina tissue in the unmodified phakic eyes .
RetinaSibling in part ofSclera
The eyes were removed at different post - injection times , frozen and dissected into anatomical subparts of cornea , aqueous , iris , lens , vitreous and sclera - choroid - retina .
However , progressive accumulation of radioactivity was observed in the sclera - choroid - retina tissue in the unmodified phakic eyes .
ScleraSibling in part ofRetina
The eyes were removed at different post - injection times , frozen and dissected into anatomical subparts of cornea , aqueous , iris , lens , vitreous and sclera - choroid - retina .
However , progressive accumulation of radioactivity was observed in the sclera - choroid - retina tissue in the unmodified phakic eyes .
ScleraNo subtypeEye
The eyes were removed at different post - injection times , frozen and dissected into anatomical subparts of cornea , aqueous , iris , lens , vitreous and sclera - choroid - retina .
However , progressive accumulation of radioactivity was observed in the sclera - choroid - retina tissue in the unmodified phakic eyes .
The eyes were removed at different post - injection times , frozen and dissected into anatomical subparts of cornea , aqueous , iris , lens , vitreous and sclera - choroid - retina .
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