Intraocular cytokine quantification of experimental autoimmune uveoretinitis in rats.

@article{Okada1998IntraocularCQ,
  title={Intraocular cytokine quantification of experimental autoimmune uveoretinitis in rats.},
  author={Annabelle Ayame Okada and Jun-ichi Sakai and Masahiko Usui and Junichiro Mizuguchi},
  journal={Ocular immunology and inflammation},
  year={1998},
  volume={6 2},
  pages={111-20}
}
Elevations of inflammatory cytokines have been implicated in the pathogenesis of experimental autoimmune uveoretinitis (EAU) in rats, although such analysis has relied on indirect methods of assessment such as measurement of mRNA content. In this study, we examined the feasibility of directly measuring cytokine concentrations in intraocular extracts prepared by ultrasonic disruption. Cytokines were measured by ELISA in eyes from EAU-induced Lewis rats immunized with interphotoreceptor retinoid… CONTINUE READING

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