Intranuclear Trafficking of RUNX / AML / CBFA / PEBP 2 Transcription Factors in Living Cells : A Dissertation

The family of runt related transcription factors (RUNX/CbfaiAML/PEBP2) are essential for cellular differentiation and fetal development. RUNX factors are distrjbuted throughout the nucleus jn punctate focj that are assocjated with the nuclear matrix/scaffold and generally correspond with sjtes of active transcrjption. Truncations of RUNX proteins that… (More)