Intranasal mupirocin to prevent postoperative Staphylococcus aureus infections

  title={Intranasal mupirocin to prevent postoperative Staphylococcus aureus infections},
  author={Trish Perl and Joseph J. Cullen and Richard P. Wenzel and Miriam Bridget Zimmerman and Michael A. Pfaller and Deborah Sheppard and Jennifer Twombley and Pamela French and Loreen A. Herwaldt},
  journal={The New England journal of medicine},
  volume={346 24},
BACKGROUND Patients with nasal carriage of Staphylococcus aureus have an increased risk of surgical-site infections caused by that organism. Treatment with mupirocin ointment can reduce the rate of nasal carriage and may prevent postoperative S. aureus infections. METHODS We conducted a randomized, double-blind, placebo-controlled trial to determine whether intranasal treatment with mupirocin reduces the rate of S. aureus infections at surgical sites and prevents other nosocomial infections… CONTINUE READING
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